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CAS NO.130209-82-4
Sales Latanoprost good supplier in China
Latanoprost is a novel anti-glaucoma drugs which is suitable for the treatment of primary open-angle glaucoma or the tropical treatment of patients of ocular hypertension which is difficult to be treated and tolerated. It also has excellent efficacy in treating pigment dispersion glaucoma, angle recession, chronic angle-closure glaucoma, uveitis and quiescent exfoliation syndrome but is invalid for treating of uveitis in its active stage.
Latanoprost is a kind of prostaglandin F2α derivative and is a kind of selective F2α receptor agonist. It is a non-active substance but can quickly penetrate into the cornea. It can be hydrolyzed into active free acid in the cornea and the plasma. It can increase the outflow amount of aqueous chambers water through the corner keratin layer. It only needs a small dose has a significant effect in boosting the outflow amount of the aqueous chambers water. The drug liquid can penetrate into the eyeball eyelashes suprachoroidal with excellent intraocular pressure lowering effect. Glaucoma will also clear the clogged trabecular mesh of patients.
Latanoprost, a phenyl-substituted prostaglandin F2α (PGF2α) analog, is a selective prostanoid FP receptor agonist. It reduces the intraocular pressure (IOP) in both animal and human subjects mainly by enhancing uveoscleral outflow. (The product is for research purpose only.)
Latanoprost is the most widely used prostaglandin for the treatment of elevated IOP in glaucoma. Latanoprost is manufactured at Cayman Chemical in Ann Arbor, MI and at Cayman Pharma, our Czech subsidiary. Both companies have a complete DMF; between the two companies the DMF/ASMF is on file with the US FDA, Canada, India, in several EU member states, and in several other countries.
Product Number | L0262 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C26H40O5 = 432.60 |
Physical State (20 deg.C) | Liquid |
Storage Temperature | <0°C |
Condition to Avoid | Heat Sensitive |
CAS RN | 130209-82-4 |
Reaxys Registry Number | 5912370 |
PubChem Substance ID | 253662165 |
Merck Index (14) | 5376 |
MDL Number |
MFCD00216074 |