Business Type:Lab/Research institutions
Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Lab/Research institutions
Tel: 86-21-58550039;86-21-31268550-8004
Mobile:
Tel: 86-21-58550039;86-21-31268550-8004
Fax: 86-21-50790419
Province/state: shanghai
City: shanghai
Street: Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China
MaxCard:
CAS NO.155206-00-1
Bimatoprost is converted by an amidase enzymatic activity in bovine and human cornea models to yield the corresponding free acid, 17-phenyl trinor PGF2α, a potent PGF2αR agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.
Catalogue Number | B386800 |
Chemical Name | Bimatoprost |
Synonyms | (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide; AGN-192024; Lumigan; Prostamide; |
CAS Number | 155206-00-1 |
Molecular Formula | C??H??NO? |
Appearance | White to Off-White Solid |
Melting Point | 64 - 65°C |
Molecular Weight | 415.57 |
Storage | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
Solubility | Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) |
Stability | Light Sensitive |
Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α. |
APIs
English Name: Bimatoprost
Other Names : Prostamide
CAS Number 155206-00-1
Molecular Formula C25H37NO4
Molecular Weight 415.27
Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. It has also been used and prescribed off-label to lengthen eyelashes.