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CAS NO.156965-06-9
Trustworthy Factory Supply 99% Pure 156965-06-9 Tisocalcitate On Stock
Tisocalcitate is a vitamin D derivative in phase 2 clinical development for treating mild to moderate psoriasis. Unlike other vitamin D3 analogues, it does not affect calcium metabolism, making it safe and well-tolerated for use on healthy skin. Tisocalcitate activates the calcium-sensing receptor by binding to its extracellular domain, inducing conformational changes, and opening ion channels. This activation has been demonstrated in cell lines and primary cells, where it also inhibits protein interactions with receptors and ligands, as well as downstream cellular signaling pathways. Although its clinical trials for psoriasis were discontinued, early studies showed promising safety and efficacy profiles. We are competent manufacturer, supplier and exporter of Tisocalcitate in China available with following details:
Specifications:
CAS No. 156965-06-9
Chemical Name: Tisocalcitate
Synonyms: Tisocalcitate
CBNumber: CB62462181
Molecular Formula: C31H48O5
Chemvon Biotechnology Co. Ltd is a high-technology pharmaceutical and fine chemical company, which is speciallized in RD, manufacturing and sales of APIs (Active Pharmaceutical Ingredients) and some organic intermediates.
With the experience and specialization in technology of asymmetric synthesis, total synthesis of natural products, organometallic reactions, chromatographic chiral separation, we supply high quality products of APIs, intermediates, speciality chemicals. and our contract services including research manufacture and custom synthesis from laboratory to commercial production are also offered on a confidential basis.
Chemvon puts great emphasis on product quality and service as followed in details:
Custom chemical services:
1. Contract custom manufacturing of intermediates and API's from microgrms up to multi tonnes scale;
2. Contract process research and upscaling studies;
3. Contract research in structure-activity of drug moleculars
Products:
1. Vitamins and steroids;
2. Organic intermediates, heterocyclic compounds including monomers of polymer materials and some building blocks;
3. Chiral synthons with multi-step reactions.
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Catalogue number: | PA 27 06488 |
Chemical name: | Tisocalcitate |
CAS Number: |
156965-06-9 |
Category: | miscellaneous compounds |
Synonyms: |
(3R,6R,E)-Isopropyl 6-((1R,3aS,7aR,E)-4-((Z)-2-((3R,5S)-3,5-Dihydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)-3-hydroxy-2,2-dimethylhept-4-enoate; (1α,3β,5Z,7E,22E,24R)-1,3,24-Trihydroxy-1-methylethyl Ester 9,10-secocholesta-5,7,10(19),22-tetraene-25-carboxylic Acid; ZK 156942; |
Molecular form: | C31H48O5 |
Appearance: | NA |
Mol. Weight: | 500.71 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |