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CAS NO.74863-84-6
Offer Reliable quality 74863-84-6 global trade Argatroban anhydrous
Argatroban is a potent inhibitor of thrombin mediated fibrinogen cleavage (Ki = 19 nM). Competitive inhibitor of thrombin-induced platelet activation and clotting. Shown to exhibit antithrombotic activity in animal models.
Chemvon Biotechnology Co. Ltd is a high-technology pharmaceutical and fine chemical company, which is speciallized in RD, manufacturing and sales of APIs (Active Pharmaceutical Ingredients) and some organic intermediates.
With the experience and specialization in technology of asymmetric synthesis, total synthesis of natural products, organometallic reactions, chromatographic chiral separation, we supply high quality products of APIs, intermediates, speciality chemicals. and our contract services including research manufacture and custom synthesis from laboratory to commercial production are also offered on a confidential basis.
Chemvon puts great emphasis on product quality and service as followed in details:
Custom chemical services:
1. Contract custom manufacturing of intermediates and API's from microgrms up to multi tonnes scale;
2. Contract process research and upscaling studies;
3. Contract research in structure-activity of drug moleculars
Products:
1. Vitamins and steroids;
2. Organic intermediates, heterocyclic compounds including monomers of polymer materials and some building blocks;
3. Chiral synthons with multi-step reactions.
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Catalogue Number | A769000 |
Chemical Name | Argatroban |
Synonyms | (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid; Argipidine; DK 7419; GN 1600; MCI 9038; MD 805; MQPA; Novastan; OM 805; Slonnon; |
CAS Number | 74863-84-6 |
Molecular Formula | C??H??N?O?S |
Appearance | White to Off-White Solid |
Melting Point | 179-185°C |
Molecular Weight | 508.63 |
Storage | -20°C Freezer |
Solubility | Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Synthetic thrombin inhibitor. Antithrombotic. |
References | Abiko, Y., et al.: Thromb. Res., 24, 285 (1981), Kikumoto, R., et al.: Biochemistry, 23, 85 (1984), |