Buy high quality Maxacalcitol cost CAS NO.103909-75-7

Min.Order: 1 Gram
Payment Terms: L/C,T/T

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ProName: Buy high quality Maxacalcitol cost
CasNo: 103909-75-7
Molecular Formula: C26H42O4
Appearance: White solid
Application: White solid
DeliveryTime: ship immediately after confirmation
PackAge: According to your demand
Port: any port in China
ProductionCapacity: Metric Ton/Day
Purity: 99
Storage: Store in a cool and dry place
Transportation: as requested
LimitNum: 1 Gram
Grade: Pharma Grade

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Maxacalcitol is the third synthetic vitamin D analog, after paricalcitol and doxercalciferol, to be marketed for the treatment of secondary hyperparathyroidism (SHPT) associated with chronic renal failure. It is a new vitamin D3 derivative with an oxygen atom in 22-position as main structural feature (22-oxacalcitriol, OCT). This vitamin D receptor agonist has a strong inhibitory effect on synthesis and secretion of parathyroid hormone in the setting of severe parathyroid hyperplasia. Maxacalcitol induced only minor effects on calcium and phosphate metabolism unlike an agent such as 1, 25(OH)2D3 that produced hypercalcemia and hyperphosphatemia. Maxacalcitol is.

22-Oxacalcitriol is the noncalcemic analogue of vitamine D and was found to suppress parathyroid hormone synthesis and secretion.22-Oxacalcitriol is a Vitamin D3 analog which is Non-calcemic as well as a VDR ligand. 22-Oxacalcitriol has been shown to decrease parathyroid hormone (PTH) mRNA expression in vitro. Additionally has been noted to exhibit similar effects to calcitriol in osteoblast-like cells. Furthermore, reported to Inhibit tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.