Keywords

• Buy Calcipotriol
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Quick Details

• ProName: Buy High quality /lowest price Calcipo...
• CasNo: 112965-21-6
• Molecular Formula: C39H68O3Si2
• Appearance: White powder
• Application: Protected trans-Calcipotriol, a vitami...
• DeliveryTime: 3-5 days after confirmation
• PackAge: According to your demand
• Port: any port in China
• ProductionCapacity: 100 Kilogram/Week
• Purity: 99%
• Storage: under nitrogen -18 degree celisus
• Transportation: as requested
• LimitNum: 1 Gram
• Grade: Pharma Grade

Superiority

Buy High quality /lowest price Calcipotriol

Calcipotriol increased hCAP18 mRNA expression in IL-17/IL-22-stimulated keratinocytes. However, LL37 peptide in the culture supernatants was reduced by calcipotriol. Calcipotriol and FTY720 augment IL-2-activated NK cell lysis of K562 and RAJI tumor cell lines as well as immature (i) and mature (m) DCs, with variable efficacies. Vitamin D3, calcipotriol and FTY720 enhance NK17/NK1 cell lysis of K562 cells, suggesting that a possible mechanism of action for these drugs is via activating these newly described cells. MC903 (calcipotriol) is a novel vitamin D3 analogue which is at least 100 times less potent than 1,25-(OH)-2-D3 in its effects on calcium homeostasis.

Name

Calcipotriene

Synonyms

(1S,3S,5Z)-5-[(2E)-2-[(1R,3aR,7aR)-1-[(E,2S)-5-Cyclopropyl-5-hydroxy-pent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol

Molecular Structure

Molecular Formula

C27H40O3

Molecular Weight

412.61

CAS Number(Or Watson Number for Non-CAS Products)

112965-21-6

EINECS

Assay, Purity or Standard

98% min

Identification

HNMR/IR

Details

Calcipotriol (INN) or calcipotriene (USAN) is a synthetic derivative of calcitriol or vitamin D. It is used in the treatment of psoriasis, marketed under the trade name "Dovonex" in the United States, "Daivonex" outside of North America, and "Psorcutan" in Germany. This medication is safe for long-term application in psoriatic skin condition.