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CAS NO.112965-21-6
High purity 98%Min /Best price Calcipotriol in bulk supply
Calcipotriene (Dovonex), a synthetic vitamin D3 derivative, is indicated for the treatment of moderate plaque psoriasis. Its mechanism of action is unknown, although it competes for calcitriol receptors on keratinocytes and normalizes differentiation. It also has a variety of immunomodulatory effects in the skin. Although the drug can cause local irritation, the most serious toxicities are hypercalciuria and hypercalcemia, which are usually reversible.
Chemvon Biotechnology is one of the leading high-technology manufacturer in the field of pharmaceutical and fine chemical industry.
From origins as a research group in technology service, chemvon has progressed into an integrated company with a kilo lab and a pilot plant offering a range of APIs, NCEs and some organic intermediates.
Quality: Adopting the leading technology to assure the high quality.
Price: Offering the best price among the suppliers in China.
Rich material and energe make us control the cost effective
Afrer-sale service: Chemvon will take charge of everthing if there is any question after the sale.
Certificates: We can offer ISO9001 certificates that you need for importing.
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Product Name |
Calcipotriol |
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CAS No. |
112965-21-6 |
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Molecular Formula |
C27H40O3 |
Molecular Weight |
412.61 |
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Batch No. |
140101 |
Mfg. Date |
Jan.10,2014 |
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Quantity |
15G |
Retest. Date |
Jan.9,2016 |
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Items |
Specifications |
Results |
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Appearance |
White or almost white crystalline powder |
Conforms |
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Identification |
a) IR |
IR chromatograph Conforms to the characteristic peak of R.S. |
Conforms |
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b) HPLC |
The retention time of the major peak in the chromatogram Conforms to the characteristic peak of R.S. |
Conforms |
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Related substances |
Known impurity |
Impurity C((5E)-calcipotriol) |
NMT1.0% |
0.60% |
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Impurity D (24-epi-calcipotriol) |
NMT1.0% |
0.40% |
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Impurity I (suprasterol of calcipotriol) |
NMT0.10% |
ND |
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Any other impurity |
NMT 0.1% |
0.09% |
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Total impurities |
NMT2.5% |
1.3% |
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Heavy metals |
<20ppm |
Conforms |
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LOD |
Not more than 1.0% |
0.4% |
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Solvent residue |
Acetone≤0.5% |
0.1% |
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Assay |
95.5~102.0% |
98.9% |
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Cat. No. :HY-10001M.Wt:412.60Formula:C27H40O3Purity:>98 %Solubility:DMSO : ≥ 100 mg/mL (242.37 mM); Ethanol : 50 mg/mL (121.18 mM; Need ultrasonic)