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CAS NO.120373-24-2
Unoprostone best price / fast delivery /on hot selling
Unoprostone isopropyl ester (Rescula) is the clinically approved, prodrug form of unoprostone, which is a free acid analog of prostaglandin F2α (PGF2α). Both latanoprost and Rescula have been approved for the treatment of ocular hypertension. Both analogs of PGF2α are believed to act by increasing the rate of aqueous humor outflow through the uveoscleral pathway. Both drugs are believed to act as prodrugs, with endogenous esterases within the eye releasing the free acid active form of the drug. The typical does of Rescula (one drop of 0.12% solution) is nearly 100 times that of latanoprost.Rescula has very little activity on isolated DP or TP receptors, less than 0.0005% the activity of PGE2 on EP3 receptors, and about 3% of the activity of PGF2α on FP receptors.
Unoprostone isopropyl ester is a free acid analog of prostoglandin F2α (sc-203219), the prodrug form of unoprostone (sc-205536). Both analogs are believed to act by increasing the rate of aqueous humor outflow through
Catalogue Number | U800050 |
Chemical Name | Unoprostone Isopropyl Ester |
Synonyms | (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopenthyl]-5-heptenoic Acid Isopropyl Ester; UF-021; Rescula; |
CAS Number | 120373-24-2 |
Molecular Formula | C??H??O? |
Appearance | Clear Colourless Oil |
Melting Point | N/A |
Molecular Weight | 424.61 |
Storage | -20°C Freezer |
Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Antiglaucoma; used in treatment of ocular hypertension. |