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Chemvon Biotechnology Co. Ltd.

Assessed Supplier Enterprise Certification

Assessed
Supplier
17th
years

Chemvon Biotechnology Co. Ltd.

Business Type:Lab/Research institutions

Audited Supplier

Main Products:
Atocalcitol ,Inecalcitol,Alvimopan ,Fosaprepitant, Bimatoprost,Lubiprostone,Tafluprost
Year Established:
2008
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Chemvon Biotechnology Co. Ltd.

Country: China (Mainland)

Business Type:Lab/Research institutions

Mr.peter

Tel: 86-21-58550039;86-21-31268550-8004

Mobile:

Tel: 86-21-58550039;86-21-31268550-8004

Fax: 86-21-50790419

URL: http://www.chemvon.com

Province/state: shanghai

City: shanghai

Street: Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China

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Buy High quality Aprepitant cost

CAS NO.170729-80-3

  • Min.Order: 1 Gram
  • Payment Terms: L/C,D/A,D/P,T/T
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Product Details

Keywords

  • Buy Aprepitant
  • High quality Aprepitant
  • Aprepitant cost

Quick Details

  • ProName: Buy High quality Aprepitant cost
  • CasNo: 170729-80-3
  • Molecular Formula: C23H21F7N4O3
  • Appearance: Off-White to Light Yellow Cyrstalline ...
  • Application: A novel selective neurokinin-1 (NK-1) ...
  • DeliveryTime: 3-5 days after conformation
  • PackAge: According to your demand
  • Port: any port in China
  • ProductionCapacity: 200 Kilogram/Week
  • Purity: 99
  • Storage: store in a tightly closed container, i...
  • Transportation: as requested
  • LimitNum: 1 Gram

Superiority

Buy High quality Aprepitant cost

Aprepitant an antiemetic and antagonist of the neurokinin-1 (NK1) receptor (Ki = 3 nM; IC50 = 0.09 nM for the human receptor). It is selective for NK1 over NK3 receptors (Ki = 454.1 nM for human NK3).1 In vivo, aprepitant (1 mg/kg) prevents plasma extravasation into the esophagus of guinea pigs induced by substance P (Item No. 24035). It also reduces NK1-agonist-induced foot tapping in gerbils. Formulations containing aprepitant have been used to prevent chemotherapy-induced nausea and vomiting.

Chemvon Biotechnology Co. Ltd is a high-technology pharmaceutical and fine chemical company, which is speciallized in RD, manufacturing and sales of APIs (Active Pharmaceutical Ingredients) and some organic intermediates.
With the experience and specialization in technology of asymmetric synthesis, total synthesis of natural products, organometallic reactions, chromatographic chiral separation, we supply high quality products of APIs, intermediates, speciality chemicals. and our contract services including research manufacture and custom synthesis from laboratory to commercial production are also offered on a confidential basis.
Chemvon puts great emphasis on product quality and service as followed in details:
Custom chemical services:
1. Contract custom manufacturing of intermediates and API's from microgrms up to multi tonnes scale;
2. Contract process research and upscaling studies;
3. Contract research in structure-activity of drug moleculars
Products:
1. Vitamins and steroids;
2. Organic intermediates, heterocyclic compounds including monomers of polymer materials and some building blocks;
3. Chiral synthons with multi-step reactions.
Welcome to you and your visit, let us make progress hand in hand!

 

Details

Catalogue Number A729800
Chemical Name Aprepitant
Synonyms 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend; L 754030; MK 0869; MK 869; ONO 7436;
CAS Number 170729-80-3
Molecular Formula C??H??F?N?O?
Appearance White to Pale Beige Solid
Melting Point 242-250°C
Molecular Weight 534.43
Storage -20°C Freezer
Solubility DMSO (Slightly), Methanol (Slightly)
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications Aprepitant is a neurokinin-1 antagonist and an antiemetic agent (1). It is used to prevent chemotherapy-induced nausea and vomiting (CINV) in colorectal cancer patients (2) Aprepitant has also been shown to induce apoptotic cell death and G1 arrest through Akt/p53 axis in pre-B acute lymphoblastic leukemia cells (3).