Keywords

• 170729-80-3 exporter
• Competitive price 170729-80-3
• Top quality 170729-80-3

Quick Details

• ProName: Competitive price /Top quality 170729-...
• CasNo: 170729-80-3
• Molecular Formula: C23H21F7N4O3
• Appearance: Off-White to Light Yellow Cyrstalline ...
• Application: A novel selective neurokinin-1 (NK-1) ...
• DeliveryTime: 3-5 days after conformation
• PackAge: According to your demand
• Port: any port in China
• ProductionCapacity: 200 Kilogram/Week
• Purity: 99
• Storage: store in a tightly closed container, i...
• Transportation: as requested
• LimitNum: 1 Gram

Superiority

Competitive price /Top quality 170729-80-3 exporter/ Aprepitant

Aprepitant is a selective high-affinity antagonist of the substance P/neurokinin 1 (NK₁) receptors. Aprepitan crosses the blood barrier, and then aprepitan occupies brain NK₁ receptors and blocks the binding of substance P to the receptors. (Substance P is a neuropeptide, acting as a neurotransmitter and as a neuromodulator.) Aprepitant has little or no affinity for serotonin (5-HT₃), dopamine, and corticosteroid receptors. Aprepitant is used for the treatment of nausea and vomiting. (The product is for research purpose only.)

Chemvon Biotechnology is one of the leading high-technology manufacturer in the field of pharmaceutical and fine chemical industry.

From origins as a research group in technology service, chemvon has progressed into an integrated company with a kilo lab and a pilot plant offering a range of APIs, NCEs and some organic intermediates.

Quality: Adopting the leading technology to assure the high quality.

Price: Offering the best price among the suppliers in China.

Rich material and energe make us control the cost effective

Afrer-sale service: Chemvon will take charge of everthing if there is any question after the sale.

Certificates: We can offer ISO9001 certificates that you need for importing.

Details

 1.Base Date

 Name:Aprepitant(mk 0869)

 CAS No.:170729-80-3

 Molecular formular:C23H21F7N4O3

 Aprepitant Chemical structure:

 2. Details of Aprepitant

 Superlist Name:Aprepitant (mk 0869)

 Molecular Formula:C23H21F7N4O3

 CAS No.:170729-80-3

 Purity:99%

 Synonyms:Aprepitant; 5-[2(R)-[1(R)-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-  fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2H-1,2,4-triazol-3-one

 Molecular Weight:534.43

 Appearance:white powder

 Aprepitant (MK-0869, L-754030) is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.