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CAS NO.170729-80-3
High purity 98%Min /Best price Aprepitant in stock
Aprepitant is a potent long-acting hNK-1 antagonist, (IC50 = 0.09 nM and Kd = 19 pM). Inhibits induced foot-tapping in gerbils. CNS penetrant and orally bioavailable. Antiemetic.
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Aprepitant | CAS 170729-80-3 | Brand: Hyper |
MW: 534.43 | MSDS: Avaiable | |
MF :C23H21F7N4O3 | Sample: Avaiable | |
Category: API | Min order: 10grams | |
Quality standard : NLT 99.0% | Place of Origin:China | |
Application | is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor. Aprepitant is manufactured by Merck & Co. under the brand name Emend for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting. |
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Technical Information | Physical State: Solid Storage: Store at -20° C Melting Point: 244-246°C (lit.) |
CAS No: | 170729-80-3 |
Synonyms: | 3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;Em end;L 754030 |
Product Code: | BA164216 |
MDL No: | MFCD08277635 |
Chemical Formula: | C23H21F7N4O3 |
Molecular Weight: | 534.43 g/mol |