Hot sale Calcifediol cost good supplier CAS NO.19356-17-3

Hot sale Calcifediol cost good supplier

Deficiency of vitamin D leads to abnormal calcium and phosphorus metabolism, contributing to deficiencies in bone formation, neuromuscular function, and inflammatory response. 25-hydroxy Vitamin D₃ is an intermediate in the pathway leading to the production of 1,25-dihydroxy vitamin D₃, the most receptor-active form of vitamin D. 25-hydroxy Vitamin D₃, produced in the liver from vitamin D₃, is metabolized in the kidney to 1,25-dihydroxy vitamin D₃. Plasma or serum levels of 25-hydroxy vitamin D₃ are commonly used as an indicator of an individual’s vitamin D status.

25-Hydroxyvitamin D3 is a major metabolite of vitamin D. Of all the circulating forms of Vitamin D3, 25-Hydroxyvitamin D3 is the principal form. 25-Hydroxyvitamin D3 can also function as a calcium regulator. 25-Hydroxyvitamin D3 is formed by hydroxylation in the liver.

A metabolite of Vitamin D. The principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator.

• Product name

  25-Hydroxyvitamin D3 (Calcifediol), metabolite of vitamin D₃

• Description

  The major circulating metabolite of vitamin D₃ (Cholecalciferol). Calcifediol also has mineralizing properties.

• Alternative names

  • Calcifediol

• Biological description

  Principal cholecalciferol (ab143594) metabolite. Downregulates TLR4 and JAK1/STAT3 signaling. Hydroxylates to calcitriol (ab141456) in vivo. Anti-inflammatory effects. Orally active.

• Purity

  > 98%

• CAS Number

  19356-17-3

• Chemical structure