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high purity Treprostinil Sodium for sale manufacturer CAS NO.289480-64-4
- Min.Order: 0 Metric Ton
- Payment Terms: L/C,T/T
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- Treprostinil Sodium for sale
- Treprostinil Sodium manufacturer
- high purity Treprostinil Sodium
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- ProName: high purity Treprostinil Sodium for sa...
- CasNo: 289480-64-4
- Application: PHARMACEUTICAL USE
- DeliveryTime: ship immediately after confirmation
- PackAge: According to your demand
- Port: any port in China
- ProductionCapacity: Metric Ton/Day
- Purity: 99
- Transportation: as requested
- LimitNum: 0 Metric Ton
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high purity Treprostinil Sodium for sale manufacturer
Treprostinil is intended for Pharmaceuticals applications. All information about Treprostinil sodium salt is provided in the MSDS. We deliver compounds with high purity levels and a comprehensive Certificate of Analysis. Connect to your member account to consult the documents.
Treprostinil is a vasodilator that is used for the treatment of pulmonary arterial hypertension. Treprostinil is a synthetic analog of prostacyclin (PGI2). The inhaled form of treprostinil was approved by the FDA in July 2009 and is marketed as the trade name Tyvaso
Treprostinil has high affinity for the DP1, EP2 and IP receptors (Ki=4.4, 3.6 and 32 nM, respectively), low affinity for EP1 and EP4 receptors and even lower affinity for EP3, FP and TP receptors. Activation of IP, DP1 and EP2 receptors, as with treprostinil, can all result in vasodilatation of human pulmonary arteries[1].Treprostinil inhibits viability of cultured endothelial colony forming cells. Endothelial colony forming cells proliferation is stimulated by conditioned media from Treprostinil pretreated mesenchymal stem cells.
Details
| Nombre del producto | Treprostinil Sodium |
|---|---|
| Sinónimos | UNII-7JZ75N2NT6; Acetic acid, (((1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((3S)-3-hydroxyoctyl)-1H-benz(f)inden-5-yl)oxy)-, monosodium salt; ({(1S,2S,3aR,9aR)-2-hydroxy-1-[(3R)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl}oxy)acetic acid; sodium ({(1S,2S,3aR,9aR)-2-hydroxy-1-[(3R)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl}oxy)acetate; sodium ({(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl}oxy)acetate |
| Fórmula molecular | C23H33NaO5 |
| Peso Molecular | 412.4949 |
| InChI | InChI=1/C23H34O5.Na/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25;/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27);/q;+1/p-1/t16-,17-,18+,19-,21+;/m0./s1 |
| Número de registro CAS | 289480-64-4 |
| Estructura Molecular | |
| Punto de ebullición | 587.1°C at 760 mmHg |
| Punto de inflamación | 199.3°C |