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CAS NO.55721-11-4
Suppliers of high purity Secalciferol in China
(24R)-24,25-Dihydroxyvitamin D3 is a vitamin D3 metabolite which is involved in bone ossification. In addition, it is known that (24R)-24,25-Dihydroxyvitamin D3 mediates calcium and phosphorus homeostasis. Also (24R)-24,25-Dihydroxyvitamin D3 inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. Alternate studies indicate that (24R)-24,25-Dihydroxyvitamin D3 can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Furthermore, (24R)-24,25-Dihydroxyvitamin D3 can increase cell proliferation in resting zone (RC) chondrocytes and inhibits matrix enzymes by possibly inhibiting the degradation of the matrix.
Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification;Anti-psoriatic.
| Catalogue Number | S211500 |
| Chemical Name | Secalciferol |
| Synonyms | (3R,6R)-2-Methyl-6-[(1R,3aS,4E,7aR)-octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-7a-methyl-1H-inden-1-yl]-2,3-heptanediol; (3β,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-3,24,25-triol; PRI 1201; (24R)-Hydroxycalcidiol; 24R,25-Dihydroxyvitamin D3; K-DR; Osteo D; |
| CAS Number | 55721-11-4 |
| Molecular Formula | C??H??O? |
| Appearance | White to Pale Yellow Solid |
| Melting Point | >81°C (dec.) |
| Molecular Weight | 416.64 |
| Storage | Amber Vial, -86°C Freezer, Under inert atmosphere |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Stability | Light Sensitive, Temperature Sensitive |
| Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Vitamin Derivatives; Vitamin D Derivatives; |
| Applications | A metabolite of Vitamin D, a possibly anti-inflammatory steroid. |
| Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |