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CAS NO.67-96-9
Dihydrotachysterol good supplier /fast delivery / in stock
Dihydrotachysterol is a synthetic analog of vitamin D. It is considered as a reduction product of vitamin D2 (ergocalciferol). It stimulates bone mineralization as well as calcium and phosphorus absorption in intestine. Dihydrotachysterol has been used for the treatment of hypoparathyroidism, osteomalacia, osteoporosis, low calcium level, and kidney osteodystrophy. Though dihydrotachysterol is more expensive, dihydrotychysterol therapy is preferred as it has a more rapid onset of action (1-7 d) and a shorter time for dissipation of effect in the event of toxicity (2-3 weeks) than vitamin D2.
Used for the prevention and treatment of rickets or osteomalacia, and to manage hypocalcemia associated with hypoparathyroidism or pseudohypoparathyroidism. Also used for the treatment of vitamin D dependent rickets, rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy, early renal osteodystrophy, osteoporosis (in conjunction with calcium), and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis).
Dihydrotachysterol is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D.
Catalogue Number | D449550 |
Chemical Name | Dihydro Tachysterol |
Synonyms | (1S,3E,4S)-4-Methyl-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-4H-onden-4-ylidene]ethylidene]cyclohexanol; (3β,5E,7E,10α,22E)-9,10-Secoergosta-5,7,22-trien-3-ol; 24-Methyl-9,10-secocholesta-5,7,22-trien-3β-ol; Antitanil; Calcamine; DHT2; Dichystrolum; Dihydral; Tachyrol; |
CAS Number | 67-96-9 |
Molecular Formula | C??H??O |
Appearance | White Solid |
Melting Point | 117-121°C |
Molecular Weight | 398.66 |
Storage | Amber Vial, -20?C Freezer |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Calcium regulator. Preparation by reduction of Tachysterol. It is widely used for hypocalcemic hypoparathyroidism following surgical removal of parathyroids. |