Keywords

• Iloprost in stock
• Iloprost immediately delivery
• Iloprost good supplier

Quick Details

• ProName: Iloprost in stock / immediately delive...
• CasNo: 78919-13-8
• Molecular Formula: C22H32O4
• Appearance: colorless oil
• DeliveryTime: ship immediately after confirmation
• PackAge: According to your demand
• Port: any port in China
• ProductionCapacity: Metric Ton/Day
• Purity: 99
• Transportation: as requested
• LimitNum: 1 Gram
• Grade: Pharma Grade

Superiority

Iloprost in stock / immediately delivery /good supplier

Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the human recombinant IP and EP₁ receptors with a K_i of 11 nM.Iloprost constricts the isolated guinea pig ilium and fundus circular smooth muscle (an EP₁ receptor preparation) as strongly as prostaglandin E₂ (PGE₂) itself.Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED₅₀ of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. It has been evaluated in several human clinical studies as a treatment for idiopathic pulmonary hypertension. In these studies, an aerosolized dose of 30 µg/day was effective, and doses as high as 150 µg/day for up to a year were well tolerated.

A synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time.

Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues.

Details

Quinone exists as a large, yellow, monoclinic prism with an irritating odor. Quinone is extensively used in the dye, textile, chemical, tanning, and cosmetic industries. In chemical synthesis for hydroquinone and other chemicals, quinone is used as an intermediate. It is also used in the manufacturing industries and chemical laboratories associated with protein fi ber, photographic fi lm, hydrogen peroxide, and gelatin making.