Keywords

• low price 93129-94-3
• Offer 93129-94-3
• high purity 93129-94-3

Quick Details

• ProName: Offer low price / high purity 93129-94...
• CasNo: 93129-94-3
• Molecular Formula: C27H44O3
• Appearance: white powder
• Application: pharm and intermediates
• DeliveryTime: According to your demand
• PackAge: as requested
• Port: any port in China
• ProductionCapacity: Metric Ton/Day
• Purity: 98%
• Transportation: as requested
• LimitNum: 0 Metric Ton
• Grade: Pharma Grade

Superiority

Offer low price / high purity 93129-94-3 / Tacalcitol monohydrate

Tacalcitol monohydrate is a VDR-like Receptor promotes normal bone development by regulating calcium. It modulates immunological and inflammatory processes and induces nerve growth factor production in epidermal keratinocytes.

Tacalcitol monohydrate (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium. IC50 value: Target: Tacalcitol modulates immunological and inflammatory processes. Tacalcitol induces nerve growth factor production in epidermal keratinocytes.

Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity. In addition, the active form of vitamin D, 1,25-dihydroxy vitamin D₃, decreases the proliferation and increases differentiation of keratinocytes.1,24-dihydroxy Vitamin D₃ is an analog of 1,25-dihydroxy vitamin D₃ which, when used in a 4 μg/g ointment, safely and effectively suppresses psoriasis. It also is effective at increasing the time interval between phototherapy cycles when ultraviolet light is used for psoriasis.1,24-dihydroxy Vitamin D₃ inhibits the growth of both normal and psoriatic human keratinocytes (IC₅₀ ~ 10 nM) via the vitamin D receptor. It also suppresses the production of RANTES and IL-8 by human dermal fibroblasts and reduces cutaneous lymphocyte-associated antigen on CD4⁺ T cells, impairing migration and skin infiltration

Details